Since 1921, Lowe's has provided every piece of hardware and home improvement equipment required by generations of Americans. It is the second-largest hardware chain in the world, in case you didn't know. And considering that Lowe's only has shops in the US and Canada, it is saying a lot! Each Lowe's location opens promptly at 6:00 AM and closes at a late hour of about 10:00 PM. Actually, Lowe's is one of the few hardware stores with such lengthy hours of operation.